Hypospadias is a common variation in fetal development of the penis in which the urethra does not open from its usual location in the head of the penis. It is the second-most common birth abnormality of the male reproductive system, affecting about one of every 250 males at birth. Roughly 90% of cases are the less serious distal hypospadias, in which the urethral opening (the meatus) is on or Other names: pronounce = /haɪpoʊˈspeɪdiəs/.
Occurrence. It is estimated that each year about 5 boys out of every 1,000 born in the United States have hypospadias, 12 making it one of the most common birth defects. Causes and Risk Factors. The causes of hypospadias in most infants are unknown.
As the etiology, or cause, of hypospadias is unknown, the goal of the Hypospadias Research Center is to define the etiology of hypospadias and to translate basic science findings into prevention or new treatment options. Accomplishing this goal requires the expertise and collaboration of scientists from multiple disciplines.